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ALT and AST, markers of liver cell damage, frequently decrease during treatment

Whilst prior failure of diet and exercise alone is not an absolute requirement for private prescription, demonstrating engagement with lifestyle changes improves outcomes and is considered best practice

Gastrointestinal adverse effects are among the most common side effects of GLP-1 agonists, including nausea, vomiting, diarrhoea, and reduced appetite

Therefore, further research is warranted to clarify the role of HSP70 in rIPC-induced renal protection, including its regulatory mechanisms and potential therapeutic implications (Figure 4)

The overlapping side effect profiles and distinct mechanisms of action create risks that may be additive or synergistic

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