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Conclusion In this work, we investigate a variety of approaches for predicting aqueous solubility and pHsolubility curves, with the goal of leveraging recent advances in pretrained molecular representations and macroscopic p K a predictions to achieve superior performance

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Highlights: New genetic study links GLP-1 receptor activation to better mental well-being Researchers found lower genetic odds of depression and bipolar disorder Experts say the findings are promising but not yet ready for clinical use medications targeting the glucagon-like peptide-1 (GLP-1) receptor, better known as GLP-1 drugs, may do more than help people lose weight or control diabetes

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