A high-cost injectable with bothersome side effects may see poor long-term adherence
Wegovy Side Effects: A Complete Guide
As of early 2026, the FDA proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B bulks list after stating it did not identify a clinical need for outsourcing facilities to compound those drugs from bulk substances
This trial, which enrolled patients with pre-existing CV disease and overweight or obesity but no diabetes, demonstrated that MACE occurred less frequently in patients taking semaglutide vs placebo (HR 0.80 [95% CI 0.720.90]
(download DOCX Summary of risk models for semaglutide (including model selection) for pooled SUSTAIN and PIONEER data
Now, researchers at Aarhus University's Department of Biomedicine have identified a possible new direction for future therapies involving GLP-1, the hormone targeted by popular weight loss medications such as Wegovy