Tirzepatide (Mounjaro) works similarly but is classified as a dual GIP/GLP-1 receptor agonist
Dose titration strategies: Gradual dose escalation represents the cornerstone of minimizing gastrointestinal adverse effects
Starting with a lower dose, it is slowly adjusted until the optimal maintenance dose is reached, allowing your body to comfortably adjust to the medication
though this is an emerging area of research and requires further exploration to substantiate such claims
Thus were the conclusions made in a 2015 paper published in Cell Metabolism , in which the authors noted that MOTS-c has physiological similarities to the first-line diabetes drug metformin with regard to managing glucose utilization, metabolism, and body weight.18 Reduced body fat Considering the effects that MOTS-c has on insulin response and glucose uptake two factors associated with weight gain the authors of the 2015 paper referenced above also examined the peptides potential for preventing obesity.19 Specifically, in a group of mice fed a high-fat diet, MOTS-c appeared to prevent obesity onset.18 Other studies have corroborated these results by finding that higher plasma MOTS-c levels are negatively correlated with obesity.20 Improved physical performance Recall that endogenous MOTS-c can be activated by exercise, allowing your skeletal muscles to use glucose for energy to meet their high energy demand
Time-restricted feeding and metabolic health: A systematic review and meta-analysis
