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In rare cases, it could be an early sign of cervical cancer
The increase in glutamine levels and the with decreased glutamate mainly in resistant cells maintained under tamoxifen indicates increased synthesis of glutamine from glutamate and decreased glutamine deamination
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Riboflavin deficiency also led to a significant increase in Kelch-like ECH-associated protein 1(Keap1) (Reference Jiang, Chen and Liu33Reference Chen, Feng and Jiang35) and decreased casein kinase 2 (CK2) mRNA level (Reference Jiang, Chen and Liu33)
