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This, he says, is why he now thinks in terms of algorithms

The bunion joint is the first joint involved in 75% of patients and is ultimately involved in over 90% of those with this condition

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Currently: BPC-157 is not FDA-approved There are no standardized treatment guidelines Long-term human safety data is lacking Large randomized clinical trials have not been completed Optimal dosing protocols have not been established Because most published research comes from animal studies, scientists cannot yet determine whether the same effects occur in humans

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In some cases it is possible to use a splint for six weeks instead of casting, and to start physical therapy once the immobilization period is over