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Retatrutide shows how doctors and patients will ultimately have a variety of drugs with different potencies to choose from, depending on their weight-loss goals and other health factors

semaglutide users receiving 0.25 mg (7%), as patients more frequently received 0.5 mg (73%) and 1.0 mg (20%)

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They cannot be taken orally unless protected because, like most peptides, they are destroyed by the enzymes and acids of the stomach