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Liu X, Liu J, Liu J et al (2013) BDNF-TrkB signaling pathway is involved in pentylenetetrazoleevoked progression of epileptiform activity in hippocampal neurons in anesthetized rats
Clinical metabolomic studies in peritoneal dialysis patients further demonstrate increased PCS and TMAO alongside reduced SCFAs, supporting the concept of a toxin accumulationSCFA depletionbarrier dysfunctionsystemic inflammation cascade (50)
Bull Exp Biol Med, 2015
Loss of redox flexibility compromises protein thiol regulation, redox-sensitive signaling pathways, and endothelial homeostasis, positioning glutathione insufficiency as a primary upstream disturbance rather than a downstream consequence of disease (1-3)
RAP-011 may alleviate anemia symptoms associated with -thal by mitigating the detrimental effects caused by GDF11 through mechanisms involving the mitigation of cellular oxidative damage and the prevention of -globin precipitation
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