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Lian et al

They activate the RAS/MAPK pathway, which promotes cell proliferation and survival (227)

The designation acknowledges safety data gaps that preclude traditional drug compounding

All had Type 2 diabetes and took either a GLP-1 or a sodium-glucose cotransporter-2 inhibitor

AOD-9604 is studied for stimulating lipolysis the breakdown of stored fat and for inhibiting lipogenesis, the formation of new fat, mimicking the way natural growth hormone signals fat cells to release energy