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6.1 MASLD and NASH Studies have shown that GLP-1RAs reduce hepatic fat content and improve liver histology in patients with MASLD, decreasing steatosis, ballooning necrosis, and liver enzyme levels

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Another study evaluating cardiovascular outcomes of GLP-1RAs was the HARMONY study

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These medications have known risks and boxed warnings , and some clinicians are appropriately cautious

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