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Landmark Trial Monday To view or add a comment, sign in GLP-1 RAs are not linked to increased risks for most serious GI or hepatobiliary outcomes compared with oral diabetes medications

Although higher doses of GLP-1R agonists alter plasma corticosterone (55), the GLP-1R agonists used in the alcohol studies were in a dose range that does not alter corticosterone in plasma (56, 57)

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TRIUMPH-1 (NCT05929066) will look at the efficacy and safety of retatrutide in people with overweight/obesity without T2D and will include subsets of participants with knee osteoarthritis (OA) or OSA

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