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The entire cassette was chemically synthesized by GENEWIZ (Suzhou, China)

Poly-L-lysine (P9155), bovine plasma fibronectin (F1141), protease type XIV (P5147), 5-bromo-2-deoxyuridine (BrdU

Collectively, these mutations promote a more compact packing both within and between protomers (Supplementary Fig

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Moreover, the current hypothesis that hydrochlorothiazide may worsen glucose homeostasis through mechanisms related to insulin secretion has been recently challenged