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The transcription factors hypoxia-inducible factor (HIF)1 and HIF2 control the physiological response to hypoxia and invoke a program of increased erythropoiesis

GLP-1, an incretin hormone, is released by enteroendocrine L-cells in the distal jejunum, ileum, and colon, where it interacts with the GLP-1R [8]

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Thrombus formation at sites of plaque rupture accounts for the majority of clinical events with acute occlusive luminal thrombosis causing myocardial infarction, unstable angina, sudden cardiac death, and stroke (168,169)

As researchers continue to explore the full potential of GLP-1 and related compounds, we can expect to see even more advanced treatments in the future

Monitoring should include regular lab testing and symptom assessment