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Some patients prefer a brief washout period

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Empower itself has faced regulatory scrutiny, with the FDA issuing warning letters as recently as April citing problems with sterile drug production and contamination controls, according to a Houston Chronicle investigation

Foods can also lead to overproduction of uric acid, such as meats and meat gravies and beer, which contain high levels of purines

The sentinel pair was observed for at least 48 h before the remaining participants were dosed, provided there were no safety or tolerability concerns as assessed by the investigator

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