The role of GLP-1 in healthcare continues to grow and evolve
Yoon S-J, Choi S-R, Kim D-M, Kim J-U, Kim K-W, Ahn C-W, et al
(88) in an 8-week randomized double-blind, placebo-controlled trial with 80 individuals experiencing episodic migraines, discovered that the combination of omega-3 PUFAs and nano-curcumin significantly reduced migraine attack frequency and serum levels of IL-1 in a synergistic manner, though the initial significant reduction in IL-1 gene expression did not remain significant after Bonferroni corrections
All four Day 1 peptides failed on multiple grounds
Older retinal reports do not meet modern confirmatory-trial standards
More recently, however, a controlled study reported no statistically significant benefit in overall Y-BOCS score, although a small, statistically significant improvement in the obsessions subscale of the Y-BOCS was found (Van Ameringen et al., 2006)