It is also important to seek advice if joint pain is accompanied by other concerning symptoms such as unexplained weight loss (beyond expected therapeutic effects), persistent fatigue, night sweats, or any signs of infection
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Phase 2 data with subcutaneous semaglutide 0.4 mg daily in noncirrhotic MASH (F1-F3) demonstrated high rates of MASH resolution but less pronounced effects on fibrosis [8]
External factors are involved in the formation of HT in addition to genetic elements
Interestingly, when patients started with a lower dose of 2 mg instead of 4 mg, the intensity of these side effects was reduced