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A large real world evidence demonstrated that when comparing several GLP-1 receptor agonists versus DPP-4 inhibitors treatments in patients with a baseline cardiovascular risk, the incidence of adverse events was much lower for the former [8]
Such work has been extended to multiple sclerosis with the CD-19 target or, more recently, with a B cell maturation antigen that extends the target to long-lived plasma cells (and dual targeting CARs vs CD19 and BCMA)
Berriat, F., Lobsiger, C
According to the GLOBOCAN 2022 report, a sharp rise in cancer cases has been observed, i.e