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10.1038/nrd.2016.153 61 WoodcockJ.LaVangeL

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This resulted in "irretrievable data".13 Regulatory Implication: 211.68(b) requires a "backup file of data." If the hardware has limited local storage, the "appropriate control" would be a validated procedure for frequent downloading and archiving of that data to a secure server before the overwrite occurs

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