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Basic hematological indices were normal except for the reticulocyte count that was increased at 6.28%

In addition to glucose (8.3 mmol l 1 ), ACh (10 mol l 1 ), and neostigmine (10 mol l 1 ), we used either Atr (Atropine,10 mmol l 1 ) or one of the selective antagonists for the M1 (pirenzepine-PZP: 100 mmol l 1 ), M2 (methoctramine MTT: 1 mmol l 1 ), and M3 (4-DAMP: 100 mmol l 1 ) mAChR subtypes

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TGF-1 signaling induces the phosphorylation of JAK2, which activates the JAK2/STAT3 signaling pathway to promote inflammatory response and fibrosis