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doi: 10.1016/S0009-8981(01)00727-6

The recommendation to cycle off is based on caution, not hard evidence

Santos-Lpez et al

doi: 10.1016/j.cmet.2018.03.001 15 World Health Organization

According to the Centers for Disease Control and Prevention (CDC), healthcare providers frequently prescribe acetaminophen instead of opioids for mild to moderate pain management, as it does not produce euphoria or cause dependence