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Shared decision-making should weigh the established benefits of semaglutide for diabetes control and weight management against theoretical thyroid risks, particularly in patients with multiple cardiovascular risk factors who stand to benefit substantially from treatment

If the bioavailability is low, most of that high dose is simply wasted

10.1038/s42255-024-01061-4 38 KnerrP

Unfortunately, factors such as genetics, environmental pollutants, and lifestyle habits can make achieving this goal difficult

May 1999;48(5):631-635

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