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Such NPs encapsulate hydrophilic and hydrophobic drugs, protect them from degradation, and enhance their delivery across the BBB (90)

Pharmacological Interactions with DMTs Given the serotonergic mechanism of action of classical PSYs such as psilocybin and LSD, their concomitant use with SSRIs, frequently prescribed in patients with depression, including those with MS may increase the risk of serotonin syndrome, especially in uncontrolled settings [15,77,123]

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