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Review of Phase II applications submitted in September 2025 was paused during the lapse in SBIR/STTR authorization

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The results of this relatively small study suggest that exercise may be an important component to minimize weight regain after GLP-1 receptor agonist discontinuation

Among other things, this is due to the fact that patients with pyruvate dehydrogenase deficiency are in a way dependent on food-derived glucose, as gluconeogenesis itself is impaired in these individuals [59]

The mean plasma homocysteine concentration, which was elevated at 10.8 mcmol/L at baseline, decreased by 39% in the active-treatment group (p=0.001 compared with the change in the placebo group)

Mytton OT, Head V, Reckless I