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A.CalendaC.CopelandC.et al (2024)

Once the PPa-GO-mAb nanoplatforms arrived in the mitochondria successfully, a 633 nm laser can kill cancer cells noticeably

Treating the deficiency can often reverse these symptoms

Product Storage Proper storage is essential for maintaining peptide stability before and after reconstitution

We observed that biobank samples (frozen within 3-17 hours) and fast-frozen in-house samples (within 1 hour) showed slight variations in metabolite levels

Overall, these findings indicate that reductions in GPx3 abundance trends with disease severity with stage 1 having the highest mean levels of GPx3 (1.99 g/ml 0.73 g/ml) and the highest K1/U1 ratio (0.86), followed by the stage 2 with a mean of 1.2 g/ml 0.54 g/ml and average K2/U2 ratio of 0.67, with the most severe form of konzo, stage 3, displaying the largest reduction in average protein abundance (mean: 1.15 g/ml 0.58 g/ml) and the lowest K3/U3 ratio of 0.59 (Supplementary Data 1)