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Tirzepatide, which acts on both GLP-1 and GIP receptors, has a similar cardiovascular profile in terms of heart rate effect

GLP-1 supplies are not guaranteed to be available at a patients pharmacy of choice and the medication may not be covered by insurance

The average cost of bariatric surgery in the United States varies widely

Waist Circumference: A significant reduction, indicating a loss of visceral fat, which is particularly harmful to health

Basu Mallik, S

The drugs' prescribing information makes that clear too: They "should be used in combination with a reduced-calorie diet and increased physical activity." And "watch what you eat" doesn't just mean cutting back on fast food