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In a landmark RCT, 174 patients with SAH were randomized to receive prednisolone with intravenous (IV) NAC (85 patients) for 5 days or prednisolone with IV 5% glucose solution (89 patients) [54]

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Why it matters: Feeling full faster can reduce intake, but it can also mask dehydration or under-eating

North America leads the first commercial wave, while parts of Europe and East Asia are likely to shape the next phase of premiumization and format innovation

Without insurance, patients typically pay the full retail price, which manufacturers often negotiate downward for insured populations through rebate arrangements