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The formation and identification of metabolites over time were analyzed using HPLC-DAD and LCMS n techniques

For example, NR3C1-1F DNA methylation was found reduced in patients with ME/CFS and coincides with the hypothalamic pituitary-adrenal (HPA) axis hypofunction hypothesis (75)

Federico A, Morgillo F, Tuccillo C, Ciardiello F & Loguercio C

showed that old erythrocytes (this means senescent erythrocytes) are more susceptible to oxidation-induced eryptosis [72]

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doi: 10.1016/j.bbadis.2019.06.001 93 LiXXuLHouXGengJTianJLiuXet al