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Both the hypotheses related to this time delay and the evolutionary specialization of M and S proteins require further investigation

Scientifically, the reduction is a process where oxygen is lost and hydrogen and electrons are gained, so reduced glutathione is missing an oxygen molecule but has an extra donor electron

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This is all based on animal models and what we understand about underlying physiology

Anand J, Chiou L, Sciandra C et al (2023) Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy

GSH system and ferroptosis in the myocardium Ferroptosis Ferroptosis is a novel form of programmed cell death characterized by the accumulation of iron-catalyzed lipid peroxidation