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Some patients may develop conditions during treatment that require caution, such as a personal diagnosis of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, which would prompt specialist review

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[DOI] [PubMed] [Google Scholar] 60.Mohy-ud-din N, Morrissey S

This result implies that MT interacts with other signal pathways as a signaling molecule, activating the TOR and calmodulin signal pathways, while inhibiting the MAPK signal pathway

This concept is still under study, but anecdotal reports and early clinical observations have sparked interest in its broader potential

Although PTX exerts significant cytotoxic effects in the treatment of advanced GC, a considerable proportion of patients develop acquired resistance to PTX during administration, ultimately leading to treatment failure 46,47