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There is a virtual catalog of speculated root causes of neurodegenerative diseases ( Neuronal activity is energetically demanding, requiring substantial amounts of adenosine triphosphate (ATP), as reflected in the disproportionate oxygen and glucose consumption of the brain compared with the rest of the body ( Various dynamic models of brain metabolism have been developed over the decades

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80 Studies of pantethine consumption have demonstrated significant reductions in total cholesterol and LDL cholesterol (up to 13.5%), triglycerides, and elevation of HDL cholesterol in people with high cholesterol 81,82 and diabetic individuals 83 when taken at 9001,200 mg/day, although significant effects on triglycerides have been observed at dosages as low as 600 mg/day

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