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The trial also flagged a new dose-dependent safety signal - dysesthesia, an abnormal nerve sensation such as tingling or burning - at 20.9% on the 12 mg arm, which will shape the label and the real-world dose pattern

The Critical Distinction Most People Are Missing Lean body mass (LBM) is not the same thing as skeletal muscle

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Recent studies have investigated the effect of dietary supplements as add-on therapy to gabapentinoids and antidepressants, as explained in the following paragraph (Table 2)