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Important Factors to Consider If youre thinking about trying a GLP-1 medication like Ozempic, Mounjaro or Wegovy, its worth looking beyond the hype

In reality, the delayed gastric emptying typically worsens reflux regardless of how much food is in the stomach

Substantial weight lossa primary effect of these medicationstypically leads to decreased blood pressure, which is generally beneficial for patients with hypertension

Recently, a real-world study showing association between incretin-based therapy and changes in taste perception with GLP-1 or dual GLP-1/GIP-RAs usage for around 40 weeks reported that independently to weight loss, there was an increase in sweet perception intensity up to 4.7 times and salt perception up to 3.2 times in around 20% of the participants, resulting as well in earlier satiety, and reduction of hunger and craving due to a major sensibilization to both flavors with any of these medication, although they did not mention further impact in weight loss or BMI change (170)

As with any observational analysis of self-selected app users, some degree of selection bias may be present

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