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The eluted peptides were ionized and detected by an inline mass spectrometer (Thermo Fisher Scientific Orbitrap Exploris 480)

However, a need exists for additional well controlled, long term human efficacy and safety studies involving p -synephrine/bitter orange extract

No other compound in development has replicated this three-receptor approach at this stage of testing

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High doses of caffeine can lead to jitteriness, increased heart rate, and anxiety