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2017, doi: 10.1056/NEJMoa1701131

Glucagon is typically stimulated by the fall in insulin during fasting in concert with low glucose levels, and responds to hypoglycaemia by mobilising hepatic glucose through the stimulation of glycogenolysis and gluconeogenesis (46)

Since ROS-dependent DNA damage is markedly increased in myeloid cells after Bcr-Abl transformation 18 , we hypothesize that blocking dTTP and dCTP supply might exacerbate replication stress and DNA damage in Bcr-Abl-transformed cells, thereby jeopardizing cell survival

TH revised the manuscript critically

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Techniques such as mindfulness, yoga, and adequate sleep can help manage stress levels