Safety and Side Effects Semaglutide, whether commercial or compounded, can cause side effects such as: Nausea Vomiting Diarrhea or constipation Fatigue Headache Serious (but rare) side effects may include: Pancreatitis Gallbladder disease Thyroid tumors (seen in animal studies) A gradual dose escalation and provider monitoring are critical to minimize risks
Clinical trial data shows average loss of approximately one percent of body weight per month during months six through twelve, ultimately reaching 15 to 16 percent total body weight loss by the end of year one
If you notice that your body is responding to your weight loss routine differently from how it used to, you may need to adjust to a change in your metabolism and adapt your diet or exercise routine
Seek support The patients who fare best are those who reach out early to their care team for help, says Dr Winnett
Effects of semaglutide on risk of cardiovascular events across a continuum of cardiovascular risk: combined post hoc analysis of the SUSTAIN and PIONEER trials
Some patients may require long-term therapy to maintain weight loss