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Initially, Furchgott called this substance endothelium-derived relaxing factor (EDRF) , but by the mid-1980s he and others identified this substance as being NO

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In particular, the extraintestinal spread of luminal microbes possessing components with structural similarity to those of the human host are thought to be involved in the breakdown of immune tolerance towards host components

Volume: 50ml (1.69 fl oz)