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( l ) Mice were treated with SANA, SAL (200 mg/kg, IP) or vehicle

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Toxicol Appl Pharmacol

2 Medications reviewed included: semaglutide, dulaglutide, tirzepatide, lixisenatide, liraglutide, and exenatide

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Regulatory T-cells express high levels of CTLA-4, and therefore may be inactivated by ipilimumab and allow effector T cell activation, causing both tumour response and colitis