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doi: 10.1007/s00125-019-4888-z 112 SinghBMouryaASahSPKumarA

Zheng XX, Li YC, Yang KL, He ZX, Wang ZL, Wang X, et al

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105 , S19S24 (2012)

Although several compounds successfully prevent coagulation of blood, each type of anticoagulant works by mediating different aspects of the coagulation pathway (i.e., heparin prevents coagulation by inhibiting the formation of thrombin, whereas EDTA prevents coagulation by chelating calcium in blood [39])

These advancements align with future CRC treatments focusing on precise NO modulation and combination regimens to overcome resistance and optimize outcomes