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AQP4 is the primary water channel in astrocytes, densely localized at perivascular end feet and critical for maintaining brain water homeostasis

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It produces more modest results than semaglutide or tirzepatide, typically around 8 percent body weight loss, but it was the first GLP-1 to receive FDA approval specifically for weight management and remains a viable option for patients who prefer a shorter-acting medication or who experience intolerable side effects on the more potent formulations

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These findings show that microbial-immune interactions have dual role, mediators and potential modulators of radiation toxicity, along the MGBA