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The signal looks real enough to take seriously

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Population pharmacokinetic modeling of VL-2397, a novel systemic antifungal agent: analysis of a single- and multiple-ascending-dose study in healthy subjects

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The Institute for Clinical and Economic Review (ICER) analysis (2025) reaffirmed that even after price drops, GLP-1s consume a large share of pharmacy budgets, though at cost-effective levels relative to benefit ( [11] )

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