As with all research compounds, investigators should implement appropriate laboratory safety protocols and follow institutional guidelines for handling investigational chemical compounds in controlled research environments
acknowledges support from the NIH (R01DK107007), the US Department of Veterans Affairs (101RX001030), the Diabetes Action Research and Education Foundation and the Baltimore Geriatric Research Education and Clinical Center (GRECC)
The quantity and purity of the RNA were assessed using an Agilent 2,100 Bioanalyzer (Agilent Technologies, United States), a NanoDrop apparatus (Thermo Fisher Scientific Inc., United States), and 1% agarose gel electrophoresis, respectively
Integration of AI and Chinese medicine databases Integrating AI with databases of Chinese medicine components offers powerful support for identifying targets of antidepressant therapies derived from traditional medicine
We found that about 20% of the metabolomic-based hepatotoxicity studies reviewed used 3D models involving either L-02 cell spheroids (Silva et al., 2013) or HLMs (Wang et al., 2019
Gut-mediated inter-organ axes Gutliver axis: a central hub of inter-organ crosstalk The gastrointestinal tract and the liver constitute two major metabolic organs in dairy cows and are functionally interconnected through a bidirectional gutliver axis mediated by multiple signaling molecules
