Typically, GLP-1 secretion in response to oral glucose is more pronounced than that in response to other administration routes 37 , suggesting a significant opportunity for future investigations to directly examine the analgesic effects of oral glucose through its impact on GLP-1 levels
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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, et al
However, electrophysiological studies revealed that GLP-1 or exendin-4 does not change the spontaneous firing activity as well as the synaptic transmission suggesting lack of functional GLP-1R in PPG neurons (Hisadome et al., 2010)
2019 Jun 13;10(6):468
Interactions between oral medications and sublingual compounds are generally minimal because they use different absorption pathways
