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Mutations in the gene encoding OCTN2, SLC22A5 , can impair fatty acid metabolism and lead to systemic primary carnitine deficiency (SPCD, OMIM 212140) 8 , an autosomal recessive disorder whose clinical manifestations include cardiomyopathy, hypoglycemia, chronic muscle weakness and liver dysfunction 9

NAD+ ( nicotinamide adenine dinucleotide ) is a coenzyme involved in cellular energy production

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