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Epidemiological evidence in some cases hints that the accepted dosages of vitamin B helps only to avoid their marginal deficiency and further benefits could accrue from higher dosages than those provided by RDA (4-5)

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[11] It results from a localized defect in the phrenoesophageal ligament while the gastroesophageal junction remains fixed to the preaortic fascia and the median arcuate ligament

Semax and NAD+ are not alternatives to each other, they are tools that address different levels of the same problem

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10 (3), R100R103