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Brzezinski A, Vangel MG, Wurtman RJ, Norrie G, Zhdanova I, Ben-Shushan A, et al

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More specifically, KEAP1 homodimerizes [124], binds to the ETGE and DLG motifs on Neh2 domain of NRF2, and also acts as a substrate adaptor protein [154] for the KEAP1-NEDD8-CUL3-RBX1 E3 ubiquitin ligase complex [119, 120, 155]