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Examples include: Wellbutrin, an antidepressant that can be used off-label for weight loss and smoking cessation Metformin, which is FDA approved to treat Type 2 diabetes and is also often used off-label for polycystic ovarian syndrome (PCOS) Contrave, a combination of Wellbutrin and naltrexone, a drug developed for the treatment of substance disorders Qsymia, a combination of the prescription weight loss drug phentermine and the anti-epilepsy drug Topamax (topiramate), which aids in weight loss when combined with a proper diet and exercise It may also decrease binge eating

Some people need injections every few months, while others may require more regular treatment

A linear BHZ concentration response was noted for 24 h and 48 h of incubation

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