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They do not demonstrate GH stimulation efficacy in healthy adults, and GI motility is a mechanistically separate effect from the pituitary GH axis that community use is predicated on

In clinical trials, about 11% of people taking Wegovy (semaglutide) reported fatigue compared to 5% of people taking the placebo

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If finalized, this would restrict the ability of 503B outsourcing facilities to compound these medications from bulk active pharmaceutical ingredients