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This Recommendation is based on results of three observational studies that used high-pressure (e.g., systolic blood pressure, mean arterial pressure) and/or long duration (e.g., repeated intervals of 30 minutes, 3 hours continuously)

The condition develops when stomach acid frequently flows back into the esophagus, creating that familiar burning sensation millions of Canadians experience regularly

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Why the literature stopped in the early 1990s DSIP research has a distinctive shape: a burst of activity from roughly 1977 to 1992, then near-silence