Nikel IP, Pettinari MJ, Galvagno MA, Mndez BS
In the TRIUMPH-1 trial, participants experienced an average weight loss of up to 28.3% over 80 weeks
Studies also demonstrate that it can be beneficial for older adults, as levels have been found to decline as we age, particularly for those with insulin resistance as it can improve sensitivity to insulin helping to reduce the risk of developing type 2 diabetes
For decades, metformin has been the go-to medication for PCOS because it improves insulin sensitivity and helps regulate cycles
A compound engineered to do the opposite, to push that pathway harder in order to grow synapses, is making a bet that you can rev a known cancer-promoting system in the brain without consequences elsewhere in the body, the same uncomfortable tradeoff we examined in our piece on whether peptides cause cancer
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