This can lower beneficial compounds like short-chain fatty acids (SCFAs), which influence everything from weight to mood and immunity, and make constipation worse if fibre and fluids arent kept up, explains BDAs Ludlam-Raine
Never discontinue tirzepatide without medical guidance, as abrupt cessation may lead to deterioration in glycemic control or weight regain
This drop-off may be attributed to a subset of patientsoften impulse buyersseeking rapid weight loss rather than committing to long-term therapeutic regimens
An interruption of just six months before resuming treatment still reduced the cardiovascular benefit, leading to a 4% to 8% increase in risk, compared to continuous use
GLP-1s vary in benefit, cause side effects, and have high dropout
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